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equilibrium binding

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  • Equilibrium unfolding — In biochemistry, equilibrium unfolding is the process of unfolding a protein or RNA molecule by gradually changing its solution conditions, i.e., its environment. Since equilibrium is maintained at all steps, the process is reversible… …   Wikipedia

  • Binding potential — In pharmacokinetics and receptor ligand kinetics the binding potential (BP) is a combined measure of the density of available neuroreceptors and the affinity of a drug to that neuroreceptor. Description Consider a ligand receptor binding system.… …   Wikipedia

  • Equilibrium constant — For a general chemical reaction:alpha A +eta B ... ightleftharpoons sigma S+ au T ...the equilibrium constant can be defined by [F.J,C. Rossotti and H. Rossotti, The Determination of Stability Constants, McGraw Hill, 1961.] :K=frac{S ^sigma {{T^ …   Wikipedia

  • Binding constant — The binding constant is a special case of the equilibrium constant K. The equilibrium state of molecular binding, i.e. the balance between the binding and dissociation processes after infinite reaction time, may be formalized as the unbound… …   Wikipedia

  • equilibrium dialysis — Technique used to measure the binding of a small molecule ligand to a larger binding partner. The macromolecule is contained within a dialysis chamber and the diffusible ligand added to the exterior: once equilibrium is reached an excess of… …   Dictionary of molecular biology

  • Binding site — In biochemistry, a binding site is a region on a protein, DNA, or RNA to which specific other molecules and ions mdash; in this context collectively called ligands, or more specifically, protein ligands mdash; form a chemical bond.The term… …   Wikipedia

  • Binding (molecular) — Molecular binding is an attractive interaction between two molecules which results in a stable association in which the two molecules are in close proximity to each other. The result of molecular binding is formation of a molecular… …   Wikipedia

  • Chemical equilibrium — In a chemical reaction, chemical equilibrium is the state in which the concentrations of the reactants and products have not yet changed with time. It occurs only in reversible reactions, and not in irreversible reactions. Usually, this state… …   Wikipedia

  • Dynamic equilibrium — For the economic concept, see Dynamic equilibrium (economics) A dynamic equilibrium exists once a reversible reaction ceases to change its ratio of reactants/products, but substances move between the chemicals at an equal rate, meaning there is… …   Wikipedia

  • Plasma protein binding — A drug s efficiency may be affected by the degree to which it binds to the proteins within blood plasma. The less bound a drug is, the more efficiently it can traverse cell membranes or diffuse. Common blood proteins that drugs bind to are human… …   Wikipedia

  • Filter binding assay — In biochemistry, one of the ways to learn about an interaction between two molecules is to determine the binding constant, which is a number that describes the ratio of unbound and bound molecules. This information reveals the affinity between… …   Wikipedia

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